Read the entire article : PCR Thermal Cycler

With the breakneck pace of the technological upgrades in our modern society, it is no wonder that the science driving a pcr thermal cycler, also known as a thermocycler, is ever improving. When looking to purchase a thermocycler for the first time or looking to upgrade your DNA testing capabilities in your laboratory, here are some features to look for in order to obtain the most cutting edge technological advancements in the field.



1.

Increased speed in temperature alterations will save you untold amounts of time in the laboratory.

2.

Look for models which provide short stabilization intervals to increase your throughput. Although it may seem trivial, this small step can save you countless hours over the lifetime of the instrument.

One of the largest factors in testing repeatability is thermocycler block uniformity. Regardless of the location where temperature measurements are taken across the block, the reading should be the same. Ensure your pcr thermal cycler has tight tolerance levels for its block uniformity.

4. Interchangeable Thermal Cycler Blocks with multiple block formats

The needs of a laboratory can be very dynamic. Be careful to ensure that your thermocycler has the capability to change out the block.

Gradient and Non-Gradient Capabilities

When you integrate gradient technology into your pcr thermal cycler will make it a much more robust instrument. This feature will undoubtedly save your laboratory tons of time by allowing you to test samples at multiple temperatures on a single run. This gradient thermal cycler feature is a must have.

6. Small Instrument Footprint

Laboratory space is limited. Don't find yourself with a gigantic bulky machine. Advancements in thermocycler technology have made it possible to drastically reduce the instrument's footprint.

7. Adequate Memory for Programming

It can be a pain programming the same protocol over and over again. Save yourself the headache by getting the proper amount of memory.

Read the entire article : PCR Thermal Cycler

The PCR Sprint Thermal Cycler remains the instrument of choice for low throughput labs requiring sub-ambient thermal cycling. It employs robust peltier technology with heating rates up to 3°C/sec with excellent uniformity and accuracy. All Hybaid Sprint PCR thermal cyclers come with an heated oil free as well as two options in thermal cycler block well formats (0.2mL x 24 and 0.5mL x 20). A huge benefit provided by the Hybaid Sprint PCR thermal cycler is the interchangable blocks. When requirements change, they are easily switched out!

The Hybaid company which has been known for its PCR Sprint thermal cycler and its PCR Express thermal cycler for years, has released its own version of block gradient thermal cycler. With an emphasis placed on maintaining temperature uniformity, Hybaid offers gradient blocks which can be fitted to the PCR thermal cycler and is capable of running gradient as well as normal thermal cycler testing. Hybaid claims the unique feature of having internal thermistors which take extremely accurate internal measurements of the true sample temperature. There are dwell time differentials between the annealing temperatures usually when determining gradient protocols for your thermal cycler. Hybaid combats this issue with its system for controlling temperature known as Active Tube as well as software which combine to accurately determine internal sample temperatures. This allows for accuracy in annealing temperatures to within a half a degree Celcius.

Watch Thermal Cycler Video >>



Material science is constantly noteworthy in regards to the conversations on new technologies. Whether the subject is synthetic polymers, silicates, or Bucky balls, there is seemingly no end to the variety of molecules that can be applied to any given problem. When engineers run out of ideas or encounter serious obstacles for improving the mechanical workings of a particular design, they frequently look at the materials they're working with to see if they can be altered to improve an existing product. Manufacturers of thermal cyclers have experimented with different metals to improve the effectiveness of their products. Typical thermal cycler blocks are produced with aluminum which is hard-anadized on its outer layer by corundum crystals, but newer versions are being made with silver-gold blocks which have been known to produce better results. Biometra and Stratagene are two of the other companies that have made the move from aluminum to silver-plated gold and nickel-plated copper..

For more info -- Hybaid Thermal Cycler

Eppendorf Scientific was first to market with a single block gradient thermal cycler, the Mastercycler® Gradient. The Mastercycler Gradient is capable of testing 12 different temperatures simultaneously across a gradient that can be set between 1-20° C. Theres is also a Mastercycler model offered without the gradient functionality. These thermal cyclers can hold 0.5/0.2 milliliter tubes, PCR plates, and cross-compatible personal memory cards. As other companies are beginning to appreciate the advantages of the gradient design, Eppendorf Scientific is looking for ways to break away from the pack.

Eppendorf Scientific has introduced a complete line of innovative consumables, a line of Taq Polymerase, and a MasterTaq kit that features a PCR enhancer that the company says gives more reproducible and robust PCR. "It is our goal to be a company that provides, one-stop shopping" for our customers' PCR needs," says Vincent Prezioso, product manager for Eppendorf. "We plan on launching many new instruments and reagents for PCR in the coming year."

For further information and product features visit Eppendorf Thermal Cycler.

The Eppendorf Mastercycler thermal cycler was the first single block gradient thermal cycler to come on the scene. With a temperature span of 20 degrees Celcius, the Eppendorf Mastercycler thermal cycer can test twelve different temperatures during a single run. Theres is also a Mastercycler model offered without the gradient functionality. These thermal cyclers can hold 0.5/0.2 milliliter tubes, PCR plates, and cross-compatible personal memory cards. Currently, the competition has begun to understand the benefits which the gradient capabilities offer to the laboratory environment, motivating Eppendorf to discover new innovations to stand out from the rest.

Eppendorf Scientific has introduced a complete line of innovative consumables, a line of Taq Polymerase, and a MasterTaq kit that features a PCR enhancer that the company says gives more reproducible and robust PCR. "It is our goal to be a company that provides, one-stop shopping" for our customers' PCR needs," says Vincent Prezioso, product manager for Eppendorf. "We plan on launching many new instruments and reagents for PCR in the coming year."

For further information and product features visit Eppendorf Thermal Cycler.

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